Have you ever think why experts talk about CBD bioavailability? Or what is CBD bioavailability, and why does it matter when picking a CBD product. The cannabis market offers a wide range of CBD-infused products; all the products have variable bioavailability.

The term of bioavailability means the amount of cannabidiol that reaches our bloodstream. It is a vital factor to consider when choosing any CBD product. Here, we will break down everything about CBD-bioavailability, from the most absorbent method to simple tips to enhance your experience.

What Is CBD Bioavailability?

You are aware of all the host ways to take CBD, from CBD oil to topicals. However, each product has a different bioavailability rate, meaning some methods allow for more absorption and potency.

The bioavailability can boost the effects of cannabinoids. If you are looking for faster action, you may choose the high bioavailability method of CBD consumption. You might be thinking increasing the milligrams equals increased strength – it can help, but bioavailability also plays a crucial role in delivering the desired CBD effects.

Let us look at the option!

Sublingual Products:


Vaping CBD is the most effective and quick way to impart therapeutic effects. Aside from vaping, sublingual ingestion of CBD oil offer much faster effects. It involves placing few CBD drops under the tongue. Our oral mucosa is full of salivary glands and tiny capillaries that absorb the CBD compound quickly, and CBD reaches the bloodstream directly.

Sublingual ingestion is a popular technique as it does not involve any equipment like vaping CBD. Also, Its fast absorption method will allow you to reap the benefits within 15 – 30 minutes. The bioavailability of sublingual CBD is 20 – 30%.

Ingestible CBD:

There is numerous ingestible CBD product like gummies, brownies, capsules, drinks, and soft-gels. One of the most discreet and original ways to take cannabinoids is CBD capsules. Moreover, You can consume CBD capsules any time, anywhere.

When you take CBD capsules, they pass through the digestive tract and liver before reaching the bloodstream. The amount of cannabidiol that reaches the bloodstream drops significantly and offers low bioavailability. On average, ingestible CBD products can deliver 13 – 19% of CBD.

Also Read: Pros and Cons of CBD Capsules

Topical CBD Products:


You might have seen various CBD topicals in the market. People use CBD topicals – lotions, creams, and balms to target specific pain areas. The ease of application and discretion has made CBD topicals quite famous among users.

Topical products applied on the skin target the cannabinoid receptors on the skin. The cannabidiol in the lotions and balm reach the bloodstream in 30 – 45 minutes. However, the rate of absorption of cannabinoids is lower than that of sublingual and ingestible products.

Vape CBD Products:  

Generally, vaping cannabidiol products offer high bioavailability values up to 10 – 60%. CBD kicks in the endocannabinoid system when you vape CBD, and you can experience the effects in 15 minutes. However, an adequate temperature is necessary when you heat the vape product.

The most commonly used CBD vape products are CBD waxes, CBD shatters, and CBD concentrates. Most people avoid vaping due to sour throat and lung infection.

What Are the Possible Ways to Enhance the Bioavailability of CBD Products?

cbd-with food

Cannabidiol or CBD is a fat-soluble compound, meaning it absorbs well with fatty acids. You can enhance the effectiveness of CBD by combining them with fatty acids. By raising the bioavailability, you can get all the therapeutic health benefits of CBD.

Here are some ways to enhance the bioavailability of cannabidiol products.

Choose A Fat Meal:

Do you think why manufacturers mix cannabidiol with a carrier oil like hemp seed oil & coconut oil? Cannabidiol has fat-soluble natures and mixes well with fatty oils. Also, You can mix CBD oil with a fat meal to enhance the absorption of cannabidiol.

Also, you can mix CBD oil with foods to boost bioavailability. However, if you are keen on CBD edibles, you may add them with a high-fat meal.


The new CBD brands in the market are using the emulsification process to break down the CBD molecules. CBD molecule breaks down into a micron size with nanotechnology. Furthermore, Emulsification can be water-based and fat-based molecule to improve bioavailability.

The emulsification of large molecules helps them to pass through the cell membrane. Moreover, Small-sized particles can cross the cell membrane at a higher rate than large molecules.

Addition of Supplemental Terpenes:

Terpenes are aromatic compounds naturally present in all types of plants. Cannabinoids are specific to cannabis plants, while terpenes and flavonoids present in other plants. Aside from imparting flavors and aroma, terpenes have potential health benefits. The addition of terpenes allows the CBD to absorbs quickly.

What Is CBD Bioavailability – Final Thoughts:

Well, that does it!

What is CBD-bioavailability, and how does it related to cannabinoids’ effects. You can choose any CBD consumption method that suits your needs and lifestyle. Also, Sublingual CBD oil is more bioavailable than any other CBD product available in the market. Before choosing, any CBD product, be assured about the reason to consume CBD.

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