CBD and the Immune System: Is CBD an Immunomodulant?

There is nothing like a pandemic that makes you think about your health. Many companies are focusing on wellness trends to provide relief to the people since the coronavirus appears. CBD and its health claims have primary importance in this arena. Millions of people have incorporated cannabidiol into their wellness regime. Some take CBD oil for pain relief and others for insomnia and other sleep issues. Some other proponents of CBD suggest that it possesses immunomodulant properties. But does it means that CBD and its relation with the immune system are effective for autoimmune disorders?

You might be wondering about using CBD as an alternative for rheumatoid arthritis – an autoimmune disorder. Every CBD user knows that CBD interacts with the endocannabinoid system that regulates various body functions. Our ECS interrelates with the immune system that controls inflammation and other conditions.

Let us explore the links between cannabidiol and immunity!

CBD for the Immune System:

Whether you are an amateur CBD user or cannabis enthusiast, knowledge about the endocannabinoid system is crucial.

Here is how our endocannabinoid system operates and its components:

• Endocannabinoids
• Cannabinoid receptors
• Enzymes

The complex cell signaling network of endocannabinoids and cannabinoid receptors is responsible for the maintenance of homeostasis. ECS also performs several bodily functions. One of the functions is its role as an immuno-cannabinoid modulator.

Communicative molecules in the ECS works as a signaling mechanism, which provides instructions for the immune responses. These instructions provide information regarding the immune system of the body and tell it when to engage in defense, how strongly to engage, and where to engage.

Can CBD Boost Your Immune System?

Your body is exposed daily to a hundred diseases, infections, viruses, and bacteria. Without an immune system, a common cold or flu can become fatal. The tissues, cells, and organs that make our immune system works together to eliminate foreign particles and invaders. The immune system eliminates foreign particles and the cells that are not working properly.

CBD & AutoImmunity:

According to researchers, the endocannabinoid system works to notify the body about incorrect body responses. An incorrect autoimmune system ends up attacking healthy tissues and organs. When you take cannabinoids to cure any autoimmune condition, it works to maintain autoimmunity.

Some autoimmune diseases are:

• Multiple sclerosis
• Rheumatoid arthritis
• Systemic lupus

Some initial research studies about CBD and the immune system are promising. However, more in-depth studies and solid shreds of evidence are crucial to proving the efficacy of cannabidiol.

CBD & Inflammation:

You might have heard about the anti-inflammatory properties of cannabidiol. Inflammation is the primary trigger of many health conditions that worsens them. Typically, when you take CBD oil or capsules, the endocannabinoids activate the cannabinoid receptors to perform body functions.

If you are suffering from any traumatic event, head injury, heart attack, or stroke, the lack of oxygen leads to inflammation that severely affects the nerve cells. Furthermore, some experts suggest that CBD can protect nerve cells from damage by reducing pain and inflammation by its anti-oxidants and anti-inflammatory properties.

Symptoms of a Weakened Immune System:

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The following are common infections found in individuals with a weakened immune system. These infections can recur with a high frequency.

• Pneumonia
• Meningitis
• Bronchitis
• Skin infection

Additionally, a person with a weakened immune system can experience:

• Autoimmune disorder
• Inflammation of internal organs
• Blood disorders
• Blood abnormalities
• Digestive problems
• Growth or development delays in infants

When it comes to inflammation, CBD can manage it, and inturns can boost your immune system. Moreover, some researchers report that the anti-inflammatory properties of CBD work as an immunosuppressant and immunomodulator.

Inflammation is the primary function managed by our immune system. The response of the immune system helps isolate and target the infected area. Also, it prevents the spreading of toxic components to other parts of the body. Cannabidiol may also be able to reduce the inflammatory response of your system.

How Does CBD Interact with the Immune System?

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Cannabidiol has some influence on the immune response, but the pathway of action is unknown. That is why healthcare professionals are unsure how to manipulate or administer CBD treatment to achieve the best results.

You might be familiar with the two primary receptors of the endocannabinoid system. CB1 receptors primarily occur in the brain and CB2 receptors in the immune system. Typically, the number of CB2 receptors is 10-100x more in the immune system. CBD interacts with these receptors to work as an immunosuppressant.

• Immunosuppressants are an agent that suppresses the immune response. They can treat psoriasis, Crohn’s disease, rheumatoid arthritis, and other health conditions.
• Immunomodulators are agents that regulate or normalize your immune system.

Cannabidiol can work both as an immunomodulator and immunosuppressant. CBD can suppress T-Cell function and production in addition to chemokines. Moreover, It encourages suppression of the immune system’s ability to remember invaders. 

Here is a quick breakdown of how CBD works as an immunosuppressant:

• CBD can promote apoptosis or cellular death
• It can prevent cell proliferation or rapid cell growth
• It can modulate or suppress the function and secretion of cytokines.
• CBD can suppress the production of chemokines
• CBD can suppress the T-Cells production and function

In general, this list looks pretty, but for a healthy person, this list contains things you want to avoid. For example, a healthy person does not want to suppress the immune response. Also, you do not want to promote cells death or stop healthy cell growth.

So, is CBD good for your immune health?

CBD work as an immunosuppressant and anti-inflammatory agent that may not a healthy choice for a healthy person. But it will be an excellent choice for a person with autoimmune disease.

Final thoughts:

If you are willing to add a health supplement to boost your immune system, CBD can provide much-needed relief. To boost your immunity and immune response, you can add CBD oil or tinctures to your health regime.

However, if you are on medications, you should always speak to your physician or healthcare professional. Also, be sure to research your chosen product.