Cannabis Entourage Effects – How CBD & THC Work Together

The cannabis plant contains more than 120 different phytocannabinoids. These phytocannabinoids possess unique properties and act on our endocannabinoid system to maintain homeostasis. You might be familiar with two well-researched and popular cannabinoids – CBD & THC.  These primary cannabinoids are responsible for Cannabis Entourage Effects.

People take CBD and THC in different ways, including oils, tinctures, capsules, edibles, and topicals. Preferably people took these phytocannabinoids separately. However, some research suggests that taking them together with small organic compounds from Cannabis Sativa is more effective than taking CBD & THC alone.

The Entourage Effects –  Interactions between phytocannabinoids and terpenes.

So, does it mean you should take CBD and THC together? Or do they work well when taken separately? Read on to learn more.

What Does The Research Say?

Taking phytocannabinoids and terpenes together may provide additional therapeutic effects. Researchers are studying various conditions in conjunction with entourage effects. British Journal of Pharmacology found that taking phytocannabinoids with terpenes may be beneficial for:

• Pain
• Anxiety
• Epilepsy
• Inflammation
• Cancer
• Fungal infection

CBD may help reduce unwanted effects of THC:

Some THC users experience hunger and sedation. However, researchers point out that CBD help reduces these side effects. In addition, the combination of CBD and THC mitigates the euphoric effects of THC.

Terpenes and Flavonoids could be beneficial for brain health:

The addition of terpenes and flavonoids with natural cannabidiol improves its therapeutic effects. Moreover, Researchers found that these essential phytocannabinoids may provide neuroprotective and anti-inflammatory effects.

Right now, the entourage effects are a well-supported theory. That is why more research and evidence are crucial. Well, this doesn’t mean that entourage effects do not exist. Simply it means that some scientifically based evidence is essential to support the theory.

What Ratio of THC to CBD is Best?

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CBD and THC work better to produce cannabis entourage effects. It is important to note that cannabis affects everyone differently, and everyone’s goals for cannabis use are different.

A person taking cannabis for Crohn’s disease will probably have a different ratio of CBD and THC than a weekend warrior who uses cannabis for muscle pain. Remember that no dosage works for everyone.

When trying CBD and THC, talk to your healthcare provider. They may be able to provide recommendations, potential drug interactions if you are taking any medications.

Another point to ponder is that CBD and THC may produce side effects. THC is a psychoactive cannabinoid that may cause:

• Fatigue
• Slow reaction time
• Dry mouth
• Short-term memory loss
• Anxiety

CBD may cause adverse effects like:

• Weight change
• Nausea
• Diarrhea

Ops! How can we forget about marijuana legality? Unfortunately, marijuana is federally illegal. If you are willing to try any product with THC to experience the Cannabis Entourage Effects, make sure to check your state marijuana laws.

Related: CBD and Drug Tests

Tips for Trying CBD and THC:

Here are some tips that work for amateur and expert cannabis consumers equally.

Start with a low dose:

• For THC – try 5 mg
• For CBD – try 5-15 mg

Experiment with timing:

Sometimes taking CBD and THC work best; you may also prefer CBD after THC as CBD will control the unwanted effects of delta-9 THC.

Try different delivery methods:

You can administer CBD and THC in various ways, including:

• Capsules
• Gummies
• Oils
• Food products
• Topicals
• Vapes

A note about vaping:

Every cannabis user cannot vape CBD or THC as vaping associates some health risks. The Center for Disease Control and Prevention recommends that people avoid THC vapes. However, if you choose to vape THC products, monitor yourself carefully. Also, visit your doctor immediately if you notice symptoms of cough, shortness of breather, and fever.

Is CBD Still Beneficial Without THC?

You might be thinking of avoiding THC due to its adverse effects. Some people avoid THC and use CBD products as they offer the same benefits as THC without any side effects.

If you are interested in trying CBD without THC, you can opt for CBD isolate products – the purest form of cannabidiol. Typically, there are three types of CBD products that are:

• CBD isolates
• Full-spectrum CBD
• Broad-spectrum CBD

Full-spectrum CBD products carry all the phytocannabinoids with less than 0.3% THC. In contrast, Broad-spectrum CBD contains all-natural cannabinoids without THC.

Before purchasing any Cannabis-infused product, check the product label for ingredients to ensure THC and other cannabinoid content.

The Takeaway:

Cannabinoids, terpenoids, and flavonoids interact with each other to produce the cannabis entourage effects. Currently, there are a few pieces of evidence that support the theory of entourage effects.

However, the Entourage effect is a theory that needs research and evidence. More research is crucial to provide authentic information about natural therapeutic chemical compounds.