By now, everyone is probably familiar with cannabinoids and their health benefits. The most prevalent chemical compounds are cannabidiol and tetrahydrocannabinol. But you likely have not heard about CBC – Cannabichromene. It is one of the big six cannabinoids that are well-researched. Though it does not get much traction, its benefits and effects are promising.
CBC is one of the third cannabinoids found in the cannabis plant. In general, the cannabis world is wide, but you have to think beyond CBD and THC. All cannabis cannabinoids have unique effects and properties.
There is plenty of information floating on the internet regarding the benefits and therapeutic effects of cannabinoids. You can start your cannabis journey by exploring the wellness advantages of these cannabinoids. Moreover, reading this article will help you understand what CBC is and how it interacts with the ECS to impart particular effects.
What Is CBC – Cannabichromene?
CBC has twenty-one carbon atoms, thirty hydrogen atoms, and two oxygen atoms. It is structurally similar to other cannabinoids such as CBD, THC, THCV, and CBN. The precursor of CBC is CBCA – Cannabichrome carboxylic acid.
Some other names of cannabichromene are:
Here is the structural formula of CBC that will help you better understand it.
Some specific enzymes cascade and breakdown the parent cannabinoid – CBG into three lines:
- CBG to THCA to THC
- CBG to CBDA to CBD
- And, CBG to CBCA to CBC
Let us explore it further!
How Does CBC Works In the Body?
You might be familiar with the endocannabinoid system and its cannabinoid receptors. In general, CBC doesn’t interact with CB1 & CB2 receptors. So, it is clear that CBC cannot produce euphoria or paranoia as with THC usage. However, CBC bind with other receptors in the body, such as vanilloid receptors 1 – TRPV1 and transient receptor potential Ankyrin 1 – TRPA1.
The activation of these TRP receptors inhibits the anandamide uptake as CBD does by increasing the amount of anandamide available in the body.
Researchers thought that CBC is ten times more potent than CBD to treat anxiety and stress symptoms. Moreover, it offers anti-inflammatory, antiviral, antitumor, and bone-growth stimulating properties.
The Medical Potentials of CBC:
The recent research studies and anecdotal evidence suggest the following health benefits of CBC. Here are some medical conditions alleviated by cannabichromene.
One study of anti-cancer effects of cannabinoids other than THC found that CBC is the second most effective cannabinoid in inhibiting the growth of new cancer cells. Moreover, the study reveals that the more potent cannabinoids are:
Typically, CBC beat cancer by increasing the amounts of anandamide in the body. However, those living with estrogen-positive breast cancer may be careful of increasing the levels of anandamide. CBC also appears to inhibit the uptake of anandamide, allowing it to remain longer in the bloodstream.
Pain and inflammation:
CBC has shown to be a specific agonist at TRPA1 channels and an inhibitor of anandamide reuptake. The therapeutic effects of CBC can block pain and inflammation associated with collagen-induced osteoarthritis.
Typically, the CBC acts on the inflammation differently than non-steroidal anti-inflammatory drugs – NSAIDs. Also, it does not have side effects similar to traditional medications. Moreover, a research study found that CBC has potent anti-inflammatory effects than CBD and THC. CBD may also desensitize the TRPV1 channel or may combine with THC or CBD to make a powerful anti-inflammatory substance.
Depression and Anxiety:
CBC could be effective in the treatment of anxiety and depression. It works in conjunction with CBD and THC to give a trifecta of anti-depressant properties. However, the therapeutic effects of CBC need more research to determine its power and efficacy. Right now, cannabis users have limited options to avail the potential benefits of cannabichromene. But the ongoing research on CBC is promising to explore its anxiolytic and other effects.
CBC for Acne:
As you know that inflammation is the root cause of acne, and the anti-inflammatory properties of CBC are promising in this regard. It can suppress the excessive lipid production in the sebaceous glands. Moreover, CBC can reduce the levels of arachidonic acid the create lipogenesis – the metabolic formation of fat. Though more research is crucial, the CBC will become a potent anti-acne treatment.
Strains of Cannabis High In CBC:
Typically, CBC – Cannabichromene is present in several varieties of cannabis. However, the following varieties contain a much higher content of CBC than normal.
- Maui Dream (Maui Wowie x Blue Dream)
- Blue Cherry Soda (precise genetics unknown, but could be a cross between Blueberry x Black Cherry Soda)
- Charlotte’s Web (a variety of hemp hailing from the Stanley Brothers)
- Purple Cadillac (Purple Urkle x The Black x Blackberry Kush)
- Bubba Cookies (Bubba Kush x Girl Scout Cookies (GSC))
- Purple Candy (Sweet Tooth x Mendocino Purps)
- Sour Tsunami (Sour Diesel x Tsunami)
The Versatile Benefits of CBC – Cannabichromene:
CBC is the third most prominent cannabinoid of the cannabis plant, but not a lot is known about it. Recent research studies report that cannabichromene can treat inflammation, acne, cancer, and a few other health conditions. Moreover, researchers have found that CBC works in tandem with CBD, THC, and other cannabinoids. Ultimately, it can boost the effectiveness of these major cannabinoids